1. The problem is to simplify the fraction $\frac{16}{4}$.\n\n2. The formula for simplifying a fraction is to divide the numerator and denominator by their greatest common divisor (GCD).\n\n3. The GCD of 16 and 4 is 4.\n\n4. Divide numerator and denominator by 4:\n$$\frac{\cancel{16}^4}{\cancel{4}^1} = \frac{4}{1}$$\n\n5. Simplifying $\frac{4}{1}$ gives 4.\n\n6. Therefore, $\frac{16}{4} = 4$.