1. **State the problem:** Simplify the expression $$(2^2 y^5)^{-2}$$.
2. **Recall the exponent rules:**
- Power of a power: $$(a^m)^n = a^{m \times n}$$
- Negative exponent: $$a^{-n} = \frac{1}{a^n}$$
- Power of a product: $$(ab)^n = a^n b^n$$
3. **Apply the power of a product rule:**
$$(2^2 y^5)^{-2} = (2^2)^{-2} (y^5)^{-2}$$
4. **Simplify each part:**
$$(2^2)^{-2} = 2^{2 \times (-2)} = 2^{-4}$$
$$(y^5)^{-2} = y^{5 \times (-2)} = y^{-10}$$
5. **Rewrite with negative exponents as fractions:**
$$2^{-4} = \frac{1}{2^4} = \frac{1}{16}$$
$$y^{-10} = \frac{1}{y^{10}}$$
6. **Combine the results:**
$$\frac{1}{16} \times \frac{1}{y^{10}} = \frac{1}{16 y^{10}}$$
**Final answer:** $$\boxed{\frac{1}{16 y^{10}}}$$
This matches answer choice A (and also E, which is the same).
Simplify Exponent 49Ca1D
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