1. **State the problem:** Evaluate the expression $ (6 \times 8 + 27) - 43 \times 5 $. 2. **Apply order of operations:** First, calculate the multiplication inside the parentheses and outside. 3. Calculate $6 \times 8 = 48$. 4. Substitute back: $ (48 + 27) - 43 \times 5 $. 5. Add inside the parentheses: $48 + 27 = 75$. 6. Substitute back: $75 - 43 \times 5$. 7. Calculate $43 \times 5 = 215$. 8. Substitute back: $75 - 215$. 9. Perform the subtraction: $75 - 215 = -140$. 10. **Final answer:** $-140$