1. The problem is to evaluate the expression for the first exercise listed: E) 4 - 6. 2. The operation is subtraction. The formula for subtraction is $a - b = c$, where $a$ and $b$ are numbers and $c$ is the result. 3. Substitute the values: $4 - 6$. 4. Calculate the difference: $4 - 6 = -2$. 5. Therefore, the answer to the first exercise E) 4 - 6 is $-2$. This completes the solution for the first problem.