1. The problem asks to fill out the genotypes of each family member in a pedigree showing the inheritance of Tay-Sachs disease, which is recessive. 2. The genotypes are defined as: - TT = normal (homozygous dominant) - Tt = carrier (heterozygous) - tt = disease (homozygous recessive) 3. Since Tay-Sachs is recessive, individuals with the disease must have genotype tt. 4. Carriers have one normal allele and one disease allele (Tt) but do not show symptoms. 5. Normal individuals have two normal alleles (TT). 6. To fill the pedigree, identify affected individuals (tt), carriers (Tt), and normals (TT) based on inheritance patterns. 7. For example, if two parents are carriers (Tt), their children have a 25% chance of being affected (tt), 50% chance of being carriers (Tt), and 25% chance of being normal (TT). 8. Use this logic to assign genotypes to each family member in the pedigree. Final answer: Genotypes assigned as TT, Tt, or tt according to the pedigree and inheritance rules of Tay-Sachs disease.