1. **State the problem:**
A 30-kg patient needs a drug dosage of 45 mg/kg/day. The drug is available as 500 mg tablets and a 200 mg/5 mL suspension.
We need to find:
(a) How many tablets the patient should take every 4 hours.
(b) The intravenous flow rate in gtt/hr using the suspension with a drop factor of 10 gtt/mL over 12 hours.
2. **Calculate total daily dosage:**
Total dosage per day = $45 \times 30 = 1350$ mg/day.
3. **(a) Tablets every 4 hours:**
There are 24 hours in a day, so doses every 4 hours means $\frac{24}{4} = 6$ doses per day.
Dosage per dose = $\frac{1350}{6} = 225$ mg per dose.
Each tablet contains 500 mg, so tablets per dose = $\frac{225}{500} = 0.45$ tablets.
4. **(b) Flow rate in gtt/hr:**
Total dosage per day = 1350 mg.
Suspension concentration = 200 mg per 5 mL, so volume needed per day = $\frac{1350}{200} \times 5 = 33.75$ mL.
Infusion time = 12 hours.
Flow rate in mL/hr = $\frac{33.75}{12} = 2.8125$ mL/hr.
Drop factor = 10 gtt/mL.
Flow rate in gtt/hr = $2.8125 \times 10 = 28.125$ gtt/hr.
**Final answers:**
(a) 0.45 tablets every 4 hours.
(b) Approximately 28 gtt/hr.
Drug Dosage 9Bc64B
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